Preoperative low skeletal muscle mass as a risk factor for pharyngocutaneous fistula and decreased overall survival in patients undergoing total laryngectomy

Autor: Thomas F. Pezier, Luuk M. Janssen, Bernard M. Tijink, Weibel W. Braunius, Sandra I. Bril, Remco de Bree
Rok vydání: 2019
Předmět:
Male
medicine.medical_specialty
Cutaneous Fistula
medicine.medical_treatment
Laryngectomy
Pharyngocutaneous Fistula
survival
Body Mass Index
sarcopenia
surgery
03 medical and health sciences
head and neck neoplasms
0302 clinical medicine
Risk Factors
Surgical oncology
postoperative complications
medicine
Humans
computer-assisted image analysis
Risk factor
Muscle
Skeletal
030223 otorhinolaryngology
Laryngeal Neoplasms
Aged
Neoplasm Staging
Retrospective Studies
body composition
business.industry
Hazard ratio
Retrospective cohort study
Original Articles
Pharyngeal Diseases
skeletal muscle mass
Length of Stay
Middle Aged
medicine.disease
Confidence interval
Surgery
Survival Rate
Otorhinolaryngology
030220 oncology & carcinogenesis
Sarcopenia
Original Article
Female
computer‐assisted image analysis
business
Zdroj: Head and Neck, 41(6), 1745. John Wiley and Sons Inc.
Head & Neck
ISSN: 1097-0347
1043-3074
DOI: 10.1002/hed.25638
Popis: Background Low skeletal muscle mass (SMM) is associated with postoperative complications, prolonged hospital stay, and short overall survival (OS) in surgical oncology. We aimed to investigate this association in patients undergoing total laryngectomy (TL). Methods A retrospective study was performed of patients undergoing TL. SMM was measured using CT or MRI scans at the level of the third cervical vertebra (C3). Results In all, 235 patients were included. Low SMM was observed in 109 patients (46.4%). Patients with low SMM had more pharyngocutaneous fistulas (PCFs) than patients with normal SMM (34.9% vs 20.6%; P = .02) and prolonged hospital stay (median, 17 vs 14 days; P
Databáze: OpenAIRE
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