The clinimetrics of hypokinesia in Parkinson's disease: Subjective versus objective assessment
| Autor: | Huub A. M. Middelkoop, J. J. van Hilten, J. I. Hoff, R. A. C. Roos |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Adult
Male medicine.medical_specialty Neurology Parkinson's disease Movement Hypokinesia Motor Activity Objective assessment Degenerative disease medicine Humans Age of Onset Geriatric Assessment Biological Psychiatry Aged Monitoring Physiologic Neurologic Examination General Neuroscience Age Factors Parkinson Disease Body movement Middle Aged medicine.disease Home setting Psychiatry and Mental health Physical therapy Neurology (clinical) Age of onset medicine.symptom Psychology |
| Zdroj: | Journal of Neural Transmission - Parkinsons Disease and Dementia Section. 8:117-121 |
| ISSN: | 1435-1463 0936-3076 |
| DOI: | 10.1007/bf02250922 |
| Popis: | In this study we evaluate the feasibility of measures that reflect different characteristics of motor activity and immobility in the objective quantification of hypokinesia. Because by definition hypokinesia can only be assessed over a period of time, continuous activity monitoring was used during 5 successive days in the home setting in 64 patients with Parkinson's disease (PD) and 104 healthy elderly subjects. In the patients we also evaluated the relation between the monitor measures and subjective measures of hypokinesia and age. Compared to the healthy elderly subjects, PD patients have a decreased activity level, increased proportion of time without movement, elevated mean duration of immobility, and decreased percentage of short-lasting immobility periods. Differences between both groups were most prominent for those measures that incorporate or reflect immobility. Moreover, in the PD patients the mean duration of immobility and percentage of short-lasting immobility periods show an apparent lack of relation with age and clinical ratings obtained from the UPDRS. In conclusion, our findings underscore the poor representation of hypokinesia in the UPDRS and value of objective quantification of this fundamental impairment of PD. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink