Epsilon-aminocaproic acid and recurrent subarachnoid hemorrhage: a clinical trial
| Autor: | S. K. Hussain, William A. Shucart, Paul R. Cooper |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Aminocaproates
medicine.medical_specialty Subarachnoid hemorrhage business.industry Intracranial Aneurysm Subarachnoid Hemorrhage medicine.disease Surgery Clinical trial Epsilon-Aminocaproic Acid Aneurysm Arterial aneurysms Recurrence Anesthesia Antifibrinolytic agent Aminocaproic Acid Medicine Drug Evaluation Humans business Recurrent hemorrhage |
| Zdroj: | Journal of neurosurgery. 53(1) |
| ISSN: | 0022-3085 |
| Popis: | ✓ A clinical trial of epsilon-aminocaproic acid (EACA) in preventing recurrent hemorrhage from intracranial arterial aneurysms is reported. Previous reports were reviewed, and their results concerning antifibrinolytic agents were inconclusive in establishing their efficacy. One hundred patients with documented ruptured intracranial aneurysms were admitted to this study within 48 hours of the initial hemorrhage: 45 patients received 36 gm of EACA/day, with 11 documented rebleeds and one suspected rebleed; 55 patients did not receive EACA, and there were four documented rebleeds and one suspected rebleed. No benefit was seen from the use of EACA. |
| Databáze: | OpenAIRE |
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