Mapping of metabolites in whole animals by 31P NMR using surface coils
| Autor: | Joseph J. H. Ackerman, D. G. Gadian, Thomas H. Grove, George K. Radda, G.G. Wong |
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| Rok vydání: | 1980 |
| Předmět: |
Metabolic state
Multidisciplinary Magnetic Resonance Spectroscopy Phosphocreatine In vivo spectroscopy Chemistry Muscles Energy metabolism Skeletal muscle High resolution Brain Hydrogen-Ion Concentration Phosphates Rats Phosphocreatine metabolism Models Structural Nuclear magnetic resonance medicine.anatomical_structure Adenosine Triphosphate Ischemia medicine Animals Energy Metabolism Radiofrequency coil |
| Zdroj: | Nature. 283(5743) |
| ISSN: | 0028-0836 |
| Popis: | The metabolic state of skeletal muscle and brain within intact rats is monitored using high resolution phosphorus nuclear magnetic resonance. Regional disturbances in metabolism (for example, localised ischaemia) are easily observed, indicating the diagnostic possibilities of the method. Measurements are made using 'surface' radiofrequency coils, which we discuss in detail. |
| Databáze: | OpenAIRE |
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