| Autor: |
Simon Fridolf, Quoc Dat Pham, Jon Pallbo, Katja Bernfur, Sara Linse, Daniel Topgaard, Emma Sparr |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Biophysical chemistry. 293 |
| ISSN: |
1873-4200 |
| Popis: |
Parkinson's disease is characterized by the aggregation of the presynaptic protein α-synuclein (αSyn), and its co-assembly with lipids and other cellular matter in the brain. Here we investigated lipid-protein co-assembly in a system composed of αSyn and model membranes containing the glycolipid ganglioside GM3. We quantified the uptake of lipids into the co-assembled aggregates and investigated how lipid molecular dynamics is altered by being present in the co-assemblies using solution |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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