EuroFIR eBASIS: application for health claims submissions and evaluations
| Autor: | Paul A. Kroon, Jenny Plumb, Jørn Gry, J C Larsen, Mairead Kiely, Lucinda J Black, Paul Finglas, Darina Sheehan, Maria Kapsokefalou, Peter C. H. Hollman, G J Speijers |
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| Rok vydání: | 2010 |
| Předmět: |
Food Safety
Knowledge management Databases Factual Medicine (miscellaneous) Nutrition Policy Information resource foods Health claims on food labels Functional food Functional Food Information system Humans Medicine polyphenols VLAG risk disease Nutrition and Dietetics Food security business.industry Food composition data Food safety Intervention studies Europe Consumer Product Safety Food Organic Plants Edible business Rikilt B&T Toxicologie en Effectanalyse Biomarkers |
| Zdroj: | European Journal of Clinical Nutrition, 64, S101-S107 European Journal of Clinical Nutrition 64 (2010) |
| ISSN: | 1476-5640 0954-3007 |
| Popis: | Background: The European Food Information Resource (EuroFIR) network has established the eBASIS (Bioactive Substances in Food Information System) online food composition and biological effects database for plant-derived bioactive compounds (phytochemicals). On the basis of submitted evidence, the European Food Safety Authority (EFSA) expert panel on Dietetic Products, Nutrition and Allergies assesses whether claims made under articles 13.1, 13.5 or 14 of the Regulation (EC) 1924/2006, which governs the use of nutrition and health claims on foods, are scientifically justified. This report evaluates the eBASIS biological effects database in the preparation and evaluation of health claims dossiers. Methods: The eBASIS biological effects database is a compilation of expert-evaluated data extracted from the literature, prioritising human intervention studies to investigate health effects of phytochemicals. Currently included are >750 records from 445 studies providing data on 56 validated biomarkers, mainly relating to cardio-metabolic and bone health outcomes. The data cover 144 bioactive compounds from 17 compound classes. Using the EFSA Register of Questions and the database of general function health claims, we identified claims relating to phytochemicals made under articles 13.1, 13.5 and 14 and compared them with the eBASIS database to identify overlap between them. Results: The EFSA online health claims database contains 4240 submissions under article 13.1, of which 2157 pertain to plants or plant-based bioactive compounds; 496 of these relate to plants or bioactive compounds included in the eBASIS biological effects database. Out of the 18 current 13.5 ‘new function’ claims on EFSA's register of questions, 7 are for plants or plant-based bioactive compounds, of which 6 are included in eBASIS. Of the 222 defined article 14 claims, 21 pertain to plants or plant-based bioactive compounds, of which 19 are in eBASIS. Conclusions: There is extensive overlap between eBASIS and the submitted health claims that relate to plant-based bioactive compounds. EuroFIR eBASIS is a useful tool for regulators to independently check completeness of health claims applications relating to phytochemicals and is a potentially valuable resource to assist claimants in the compilation of dossiers on functional foods and health claims. |
| Databáze: | OpenAIRE |
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