Skin-Related complications of Klippel-Trenaunay Syndrome: a retrospective review of 410 patients
| Autor: | Christine M. Lohse, Megha M. Tollefson, David J. Driscoll, Katelyn R. Anderson, Henry L. Nguyen, Jennifer J. Schoch |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Klippel-Trenaunay-Weber Syndrome Klippel-Trenaunay syndrome Vascular Malformations Dermatology Vascular anomaly 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Ectasia Medicine Humans Buttocks Retrospective Studies Lymphatic Abnormalities business.industry Vascular malformation medicine.disease Perineum Surgery Capillaries Infectious Diseases medicine.anatomical_structure 030220 oncology & carcinogenesis Cellulitis business Venous malformation |
| Zdroj: | Journal of the European Academy of Dermatology and Venereology : JEADVReferences. 35(2) |
| ISSN: | 1468-3083 |
| Popis: | BACKGROUND Little is known about skin-related complications in Klippel-Trenaunay syndrome (KTS), a complex vascular anomaly defined by capillary malformation (CM), venous malformation (VM) ± lymphatic malformation (LM) and limb overgrowth. Reported skin-related complications of KTS include ulceration, vascular ectasias (blebs), bleeding and infection. OBJECTIVE To determine the spectrum, prevalence and predictors of skin-related complications in KTS. METHODS A retrospective review of 410 patients fulfilling KTS criteria was performed to assess for the presence of skin-related complications. RESULTS Skin-related complications were present in 45% of patients. Most prevalent were CM-related complications including blebs, bleeding, thickening (25%), cellulitis (22%) and ulceration (21%). Features positively associated with skin-related complications were presence of LM (OR 17.17; P |
| Databáze: | OpenAIRE |
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