Preoperative evaluation of malignant liver tumors: comparison of unenhanced and SPIO (Resovist)-enhanced MR imaging with biphasic CTAP and intraoperative US
| Autor: | Michael Pietsch, Renate Hammerstingl, Roland Felix, Thomas J. Vogl, Kohkan Shamsi, Kelly Del Tredici, Peter Neuhaus, W. Schwarz, Hartmut Lobeck, Stefan Blume, Martina Franz, Thomas Balzer |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Adult
Male medicine.medical_specialty Carcinoma Hepatocellular Iron Contrast Media Sensitivity and Specificity Lesion Carcinoma medicine Humans Radiology Nuclear Medicine and imaging Magnetite Nanoparticles Portography Aged Ultrasonography Neuroradiology Aged 80 and over Observer Variation medicine.diagnostic_test business.industry Liver Neoplasms Ultrasound Dextrans Oxides Magnetic resonance imaging Interventional radiology General Medicine Middle Aged Image Enhancement medicine.disease Magnetic Resonance Imaging Ferrosoferric Oxide Bile Ducts Intrahepatic Bile Duct Neoplasms Liver Injections Intravenous Female Radiology Tomography medicine.symptom business Tomography Spiral Computed |
| Zdroj: | European Radiology. 13:262-272 |
| ISSN: | 1432-1084 0938-7994 |
| DOI: | 10.1007/s00330-002-1677-7 |
| Popis: | The purpose of this study was to evaluate the diagnostic efficacy of iron-oxide-enhanced MRI vs CT during arterial portography (CTAP) and intraoperative ultrasound (IOUS) in detection of liver neoplasms. Seventeen patients with malignant focal liver lesions (liver metastases, n=7), hepatocellular carcinomas (HCC, n=9), and cholangiocellular carcinoma (CCC, n=1) underwent presurgical Resovist-enhanced MRI and CTAP. Two independent observers (A and B) assessed the blinded images of unenhanced and iron-oxide-enhanced MRI vs CTAP for the presence, number, and location of the liver lesions. These results were compared lesion by lesion and segment by segment with the results of intraoperative ultrasound ( n=17) serving as the reference standard. Eighty lesions were detected by intraoperative ultrasound in 17 patients. In comparison with IOUS (lesion-by-lesion analysis) the sensitivity was 86.8% for CTAP, 65% for combined unenhanced MR imaging, and 86.8% for combined Resovist-enhanced MRI as well as 86.8% for the combination of unenhanced and Resovist-enhanced MRI. Compared with the sensitivity of combined unenhanced MRI the sensitivity of CTAP as well as the sensitivity of combined Resovist-enhanced MRI was significantly higher (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink