Risk factor for wound complications following wide resection of soft tissue sarcoma in the adductor compartment of the thigh
| Autor: | Hirotaka Koyanagi, Keisuke Ae, Masanori Okamoto, Akira Takazawa, Kaoru Aoki, Munehisa Kito, Yasuo Yoshimura, Tabu Gokita, Shuichiro Suzuki, Hideto Furuoka, Atsushi Tanaka |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Cancer Research Surgical margin medicine.medical_specialty Adolescent Femoral artery Thigh Young Adult 03 medical and health sciences 0302 clinical medicine Risk Factors medicine.artery Humans Medicine Radiology Nuclear Medicine and imaging Child Vein Aged Aged 80 and over 030222 orthopedics Univariate analysis business.industry Muscles Soft tissue sarcoma Sarcoma General Medicine Middle Aged medicine.disease Intraoperative Hemorrhage Magnetic Resonance Imaging Surgery Logistic Models medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis Wounds and Injuries Female business |
| Zdroj: | Japanese Journal of Clinical Oncology. 49:932-937 |
| ISSN: | 1465-3621 |
| DOI: | 10.1093/jjco/hyz101 |
| Popis: | BackgroundThe purpose of this study was to investigate deep-seated soft tissue sarcoma (STS) occurring in the adductor compartment of the thigh that underwent wide resection and to clarify the high-risk group for wound complications.Patients and methodsFrom 2000 to 2017, we reviewed 104 cases of deep-seated STS occurring in the adductor compartment of the thigh that were treated at four specialized facilities with expertise in sarcoma treatment.ResultsWound complications occurred in 40 cases (38.5%), of which 23 cases (22.1%) were cases with major wound complications (MWC). In univariate analysis, BMI (P < 0.01), maximum tumor diameter (P < 0.01), operation time (P < 0.01), amount of intraoperative bleeding (P < 0.01), and intraoperative intervention to the femoral artery and vein (P < 0.01) were significantly associated with wound complications. In multivariate analysis, the associated parameters were BMI (P < 0.01), maximum tumor diameter (P = 0.02), and intraoperative intervention to the femoral artery and vein (P = 0.01). When limited to cases with MWC, univariate analysis showed that maximum tumor diameter (P < 0.01), diabetes mellitus (P = 0.03), operation time (P < 0.01), amount of intraoperative bleeding (P < 0.01), and intraoperative intervention to the femoral artery and vein (P = 0.02) were significantly associated parameters. In multivariate analysis, maximum tumor diameter (P = 0.02) and amount of intraoperative bleeding (P = 0.04) were associated parameters.ConclusionsFor patients with risk factors for wound complications, control of bleeding are crucial when resecting deep-seated STS in the adductor compartment of the thigh. In cases with large tumors, surgeons should be especially cautious of cases requiring interventions that surround the femoral artery and vein in order to attain an appropriate surgical margin. |
| Databáze: | OpenAIRE |
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