HNF1A gene p.I27L is associated with co-existing preeclampsia in gestational diabetes mellitus

Autor: Sema Hepsen, Ali Alhan, Selvihan Beysel, Seyfullah Kan, Muhammed Kizilgul, Erhan Bozkurt, Mustafa Caliskan, Ferda Alparslan Pinarli, Erman Cakal, Nilnur Eyerci
Rok vydání: 2019
Předmět:
Adult
medicine.medical_specialty
endocrine system diseases
Genotype
Turkey
Endocrinology
Diabetes and Metabolism

030209 endocrinology & metabolism
Comorbidity
FTO gene
Polymorphism
Single Nucleotide

Preeclampsia
03 medical and health sciences
Young Adult
0302 clinical medicine
Endocrinology
Gene Frequency
Pre-Eclampsia
Leucine
Pregnancy
Internal medicine
medicine
Humans
Genetic Predisposition to Disease
Hepatocyte Nuclear Factor 1-alpha
Isoleucine
Gene
030219 obstetrics & reproductive medicine
business.industry
nutritional and metabolic diseases
Obstetrics and Gynecology
pathological conditions
signs and symptoms

medicine.disease
female genital diseases and pregnancy complications
Gestational diabetes
Diabetes
Gestational

Amino Acid Substitution
Case-Control Studies
Female
business
HNF1A Gene
Zdroj: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 36(6)
ISSN: 1473-0766
Popis: The association of the FTO gene and HNF1α gene on gestational diabetes mellitus (GDM) and preeclampsia remains unclear. This is the first study to examine whether HNF1α gene and FTO gene were associated with having GDM and preeclampsia in Turkish women. Healthy pregnant women (
Databáze: OpenAIRE