Estimating burden of influenza-associated influenza-like illness and severe acute respiratory infection at public healthcare facilities in Romania during the 2011/12-2015/16 influenza seasons

Autor: Christiaan Dolk, Giedre Gefenaite, Diane Gross, Adriana Pistol, Odette Popovici, Mark Jit, Daniel Ciurea, Rodica Popescu
Přispěvatelé: PharmacoTherapy, -Epidemiology and -Economics
Jazyk: angličtina
Rok vydání: 2018
Předmět:
0301 basic medicine
Pulmonary and Respiratory Medicine
Adult
Pediatrics
medicine.medical_specialty
Time Factors
Adolescent
Epidemiology
Population
Annual incidence
Public healthcare
burden
03 medical and health sciences
0302 clinical medicine
Severe acute respiratory infection
Cost of Illness
Influenza
Human
Journal Article
Medicine
Humans
030212 general & internal medicine
education
Child
Disease burden
Aged
Influenza-like illness
education.field_of_study
influenza‐like illness
business.industry
Romania
Incidence (epidemiology)
Public Health
Environmental and Occupational Health
Infant
Newborn
Infant
virus diseases
Original Articles
Middle Aged
030112 virology
Confidence interval
Hospitalization
Infectious Diseases
Child
Preschool
Emergency medicine
Original Article
Health Facilities
Seasons
business
severe acute respiratory infection
Sentinel Surveillance
Zdroj: Influenza and other respiratory viruses, 12(1), 183-192. Wiley
Influenza and Other Respiratory Viruses
ISSN: 1750-2640
Popis: BACKGROUND: Influenza is responsible for substantial morbidity and mortality, but there is limited information on reliable disease burden estimates, especially from middle-income countries in the WHO European Region.OBJECTIVES: To estimate the incidence of medically attended influenza-associated influenza-like illness (ILI) and hospitalizations due to severe acute respiratory infection (SARI) presenting to public healthcare facilities in Romania.PATIENTS/METHODS: Sentinel influenza surveillance data for ILI and SARI from 2011/12-2015/16, including virological data, were used to estimate influenza-associated ILI and SARI incidence/100 000 and their 95% confidence intervals (95% CI).RESULTS: The overall annual incidence of ILI and influenza-associated ILI per 100 000 persons in Romania varied between 68 (95% CI: 61-76) and 318 (95% CI: 298-338) and between 23 (95% CI: 19-29) and 189 (95% CI: 149-240), respectively. The highest ILI and influenza incidence was among children aged 0-4 years. We estimated that SARI incidence per 100 000 persons was 6 (95% CI: 5-7) to 9 (95% CI: 8-10), of which 2 (95% CI: 1-2) to 3 (95% CI: 2-4) were due to influenza. Up to 0.3% of the Romanian population were annually reported with ILI, and 0.01% was hospitalized with SARI, of which as much as one-third could be explained by influenza.CONCLUSIONS: This evaluation was the first study estimating influenza burden in Romania. We found that during each influenza season, a substantial number of persons in Romania suffer from influenza-related ILI or are hospitalized due to influenza-associated SARI.
Databáze: OpenAIRE
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