Trend analysis of carbapenem-resistant Gram-negative bacteria and antimicrobial consumption in the post-COVID-19 era: an extra challenge for healthcare institutions
| Autor: | Carlos Magno Castelo Branco Fortaleza, João Paulo Telles, Cristina Pellegrino Baena, Felipe Francisco Tuon, Patrícia de Jesus Capelo, Viviane Maria de Carvalho Hessel Dias |
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| Přispěvatelé: | Pontifícia Universidade Católica do Paraná, State Health Department of Paraná, Universidade Estadual Paulista (UNESP), Hospital Marcelino Champagnat |
| Rok vydání: | 2021 |
| Předmět: |
Antimicrobial drug resistance
Microbiology (medical) Acinetobacter baumannii Gram-negative bacteria medicine.drug_class Polymyxin Short Report Microbial Sensitivity Tests Healthcare-associated infections Anti-Infective Agents Drug Resistance Multiple Bacterial Environmental health Drug Resistance Bacterial Gram-Negative Bacteria Antimicrobial stewardship Infection control Medicine Humans Polymyxins Pandemics biology business.industry SARS-CoV-2 Incidence (epidemiology) COVID-19 Bacterial Infections General Medicine Antimicrobial Drug Resistance biology.organism_classification Antimicrobial Hospitals Anti-Bacterial Agents Trend analysis Infectious Diseases Carbapenems business Delivery of Health Care |
| Zdroj: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP The Journal of Hospital Infection |
| ISSN: | 1532-2939 |
| Popis: | Made available in DSpace on 2022-04-28T19:48:30Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-02-01 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Ministério da Educação The incidence density trend of the carbapenem-resistant Gram-negative bacteria was analysed in device-associated infections and antimicrobial consumption in 99 critical care facilities in a low/middle-income country, between January 2019 and December 2020. Carbapenem-resistant Acinetobacter baumannii (CRAB) per 1000 patient-days increased in 2020 and this finding had a strong positive correlation with the incidence density of COVID-19 by the Spearman test. Polymyxin consumption also increased in 2020 but without significant correlation with CRAB or COVID-19 incidence density, presumably due to empirical and untargeted prescribing as a consequence of concern about CRAB infections. These findings are a warning to infection control programmes and antimicrobial stewardship. School of Medicine Pontifícia Universidade Católica do Paraná Laboratory of Emerging Infectious Diseases Pontifícia Universidade Católica do Paraná State Health Department of Paraná Universidade Estadual Paulista (UNESP) Hospital Marcelino Champagnat Universidade Estadual Paulista (UNESP) |
| Databáze: | OpenAIRE |
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