A Comparative Study of Loratadine Syrup and Cyproheptadine HCL Solution for Treating Perennial Allergic Rhinitis in Taiwanese Children Aged 2–12 Years
| Autor: | Li Th, Keh-Gong Wu, Chun-Jen Chen, Wang Ty, Chien-Lun Hsu |
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| Rok vydání: | 2012 |
| Předmět: |
Male
Histamine H1 Antagonists Non-Sedating Rhinitis Allergic Perennial Immunology Cyproheptadine Taiwan Loratadine law.invention Loratadine syrup Randomized controlled trial law Humans Immunology and Allergy Medicine Child Pain Measurement Pharmacology business.industry Treatment efficacy Solutions Child Preschool Anesthesia Histamine H1 Antagonists Female Cyproheptadine hcl business medicine.drug |
| Zdroj: | International Journal of Immunopathology and Pharmacology. 25:231-237 |
| ISSN: | 2058-7384 |
| DOI: | 10.1177/039463201202500125 |
| Popis: | We assessed the efficacy of loratadine syrup compared with cyproheptadine HCl solution for treating children aged from 2 to 12 years with perennial allergic rhinitis (PAR) in Taiwan. Sixty children with mite-induced PAR were enrolled and randomly placed into two treatment groups: loratadine syrup or cyproheptadine HCl solution. Treatment efficacy and symptom changes from baseline to post-treatment were evaluated by total symptom scores and visual analogue scales (VAS) during a 2-week period. There were no differences in age, gender, height, or weight between the two groups. After 2 weeks of treatment, there was a significantly greater reduction in symptom scores in the loratadine group than in the cyproheptadine group ( p |
| Databáze: | OpenAIRE |
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