Ellagic acid inhibits proinflammatory intermediary manufacture by suppressing NF-κB/Akt, VEGF and activating Nrf-2/Caspase-3 signaling pathways in rat testicular damage: a new way for testicular damage cure and in silico approach

Autor:	Abdullah Aslan, Ozlem Gok, Seda Beyaz, Harun Uslu, Fazilet Erman, Orhan Erman, Serpil Baspinar
Rok vydání:	2022
Předmět:	Vascular Endothelial Growth Factor A Caspase 3 Tumor Necrosis Factor-alpha Health Toxicology and Mutagenesis NF-kappa B Toxicology Glutathione Rats Oxidative Stress Ellagic Acid Proto-Oncogene Proteins c-bcl-2 Animals Proto-Oncogene Proteins c-akt Signal Transduction
Zdroj:	Toxicology Mechanisms and Methods. 32:463-476
ISSN:	1537-6524 1537-6516
DOI:	10.1080/15376516.2022.2046668
Popis:	Ellagic acid (EA) has protective effect on testicular damage and this natural compound decreases oxidative damage. The present study aims to examine the preventive effect of ellagic acid (EA) against carbon tetrachloride (CCl
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec1f7e59ff76cec75050bbe59917ca5b https://doi.org/10.1080/15376516.2022.2046668 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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