Obsessive-compulsive symptom dimensions: Association with comorbidity profiles and cognitive-behavioral therapy outcome in pediatric obsessive-compulsive disorder
| Autor: | Tord Ivarsson, Gudmundur Skarphedinsson, Nor Christian Torp, Katja A. Hybel, Robert Valderhaug, Eric A. Storch, Judith Becker Nissen, Davíö R.M.A. Højgaard, Kitty Dahl, Karin Melin, Per Hove Thomsen, Bernhard Weidle, Erik Lykke Mortensen |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Obsessive-Compulsive Disorder Adolescent Sexual Behavior medicine.medical_treatment Comorbidity Hoarding Affect (psychology) behavioral disciplines and activities 03 medical and health sciences 0302 clinical medicine mental disorders Odds Ratio Humans Medicine 0501 psychology and cognitive sciences Child Association (psychology) Biological Psychiatry Cognitive Behavioral Therapy business.industry 05 social sciences Schedule for Affective Disorders and Schizophrenia Odds ratio Prognosis medicine.disease Outcome (probability) Latent class model 030227 psychiatry Cognitive behavioral therapy Psychiatry and Mental health Logistic Models Treatment Outcome Female business 050104 developmental & child psychology Clinical psychology |
| Zdroj: | Aarhus University Højgaard, D R M A, Hybel, K A, Mortensen, E L, Ivarsson, T, Nissen, J B, Weidle, B, Melin, K, Torp, N C, Dahl, K, Valderhaug, R, Skarphedinsson, G, Storch, E A & Thomsen, P H 2018, ' Obsessive-compulsive symptom dimensions : Association with comorbidity profiles and cognitive-behavioral therapy outcome in pediatric obsessive-compulsive disorder ', Psychiatry Research, vol. 270, pp. 317-323 . https://doi.org/10.1016/j.psychres.2018.09.054 Højgaard, D R M A, Hybel, K A, Mortensen, E, Ivarsson, T, Nissen, J B, Weidle, B, Melin, K, Torp, N C, Dahl, K, Valderhaug, R, Skarphedinsson, G, Storch, E A & Thomsen, P H 2018, ' Obessive-compulsive symptom dimensions: Association with comorbidity profiles and cognitive-behavioral therapy outcome in pediatric obsessive-compulsive disorder ', Nordic Congress of Psychiatry (NCP) 2018, Reykjavik, Iceland, 01/06/2018 . |
| ISSN: | 0165-1781 |
| DOI: | 10.1016/j.psychres.2018.09.054 |
| Popis: | Our aims were to examine: (1) classes of comorbid disorders in a sample of children and adolescents with Obsessive-Compulsive Disorder (OCD), (2) how these classes relate to obsessive-compulsive symptom dimensions, and (3) the extent to which obsessive-compulsive symptom dimensions predict Cognitive-Behavioral Therapy (CBT) outcome. Participants (N = 269) were assessed with the Kiddie Schedule for Affective Disorders and Schizophrenia (K-SADS-PL) and the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS). Latent Class Analysis (LCA) was used to identify comorbidity classes. Regression analyses were used to evaluate symptom dimensions as predictors of treatment outcome and their relation to comorbidity classes. Comorbidity was included in the treatment outcome analyses as it can affect outcome. Comorbidity was best categorized by a three-class model and each class was distinctively correlated with the OCD symptom dimensions. Higher scores on the symmetry/hoarding factor increased the chance of responding to CBT by an odds ratio of 1.56 (p = 0.020) when controlled for age, gender, and comorbidity class. The harm/sexual factor (p = 0.675) and contamination/cleaning factor (p = 0.122) did not predict CBT outcome. Three clinically relevant comorbidity subgroups in pediatric OCD were identified. Patients who exhibited higher levels of symmetry/hoarding dimension were more prone to respond to CBT. |
| Databáze: | OpenAIRE |
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