929-63 Dobutamine Stress Cine Magnetic Resonance Imaging versus PET for Detection of Myocardial Viability
| Autor: | Xavier André-Fouët, Roland Itti, Claire Baldy, Didier Revel, Sameh Bakhoum, Valérie Julien, Marc Janier, Michel Ovize |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry Fdg uptake Magnetic resonance imaging Dobutamine stress medicine.disease Internal medicine Computer software medicine Quantitative assessment Cardiology Dobutamine Wall motion Myocardial infarction Nuclear medicine business Cardiology and Cardiovascular Medicine medicine.drug |
| Zdroj: | Journal of the American College of Cardiology. 25(2) |
| ISSN: | 0735-1097 |
| DOI: | 10.1016/0735-1097(95)91922-k |
| Popis: | To identify viable myocardium before coronary revascularization, we prospectively submitted eleven patients (60 ± 7 yrs; 11 M) with previous Q-wave myocardial infarction to 18 FDG-Positon Emission Tomography and low-dose (5 to 10 μg/kg/min) dobutamine cine-MRI. 18 FDG uptake g 60% was considered indicative of viable tissue. Ouantitation of systolic wall thickening/thinning (SW) was performed by use of a computer software allowing automatic detection of epicardial and endocardial outlines, at rest and under 5, 7.5 and 10 μg/kg/min of dobutamine. Heart slices of both 18 FDG-PET scans and dobutamine cine-MRI were divided in 8 segments, matched and analyzed byobservers blinded to clinical data. Sixty-five segments were considered viable by 18 FDG-PET; in this subgroup, rest SW thickening averaged 47 ± 5% and improved by 43 ± 8% under low-dose dobutamine. In the remaining 23 segments considered non viable by PET. rest SW thickening averaged 14 ± 7% * ( * p l 0.05 vs viable segment group) and further worsened by –13 ± 8% * during low-dose dobutamine stress ( * p l 0.05 versus viable segment group). Positive predictive value of low-dose dobutamine stress cine-MRI for assessment of myocardial viability was 84%. These data suggest that quantitative assessment of regional wall motion by dobutamine cine-MRI may help discriminate viable from non viable myocardium as defined by 18 FDG-Positon Emission Tomography. |
| Databáze: | OpenAIRE |
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