Increasing The Packing Density Of Assays In Paper-Based Microfluidic Devices

Autor: Mehmed Ozkan, Hayati Havlucu, Sajjad Rahmani Dabbagh, Ali K. Yetisen, Fariba Ghaderinezhad, Oğuzhan Özcan, Savas Tasoglu, Elaina M. Becher
Rok vydání: 2021
Předmět:
Biochemistry & Molecular Biology
Fabrication
Computer science
FLOW
Microfluidics
Biophysics
FABRICATION
Biomedical Engineering
02 engineering and technology
0915 Interdisciplinary Engineering
01 natural sciences
Biochemical Research Methods
0203 Classical Physics
Colloid and Surface Chemistry
Physics
Fluids & Plasmas
Fabrication methods
IMMUNODEVICE
Hardware_INTEGRATEDCIRCUITS
General Materials Science
Nanoscience & Nanotechnology
Process engineering
Review Articles
Fluid Flow and Transfer Processes
Science & Technology
COLORIMETRIC DETECTION
1007 Nanotechnology
business.industry
Physics
010401 analytical chemistry
RAPID DETECTION
LOW-COST
SENSOR
PATTERNED PAPER
Paper based
021001 nanoscience & nanotechnology
Condensed Matter Physics
LAB-ON-PAPER
0104 chemical sciences
Sphere packing
Physical Sciences
Science & Technology - Other Topics
0210 nano-technology
business
Life Sciences & Biomedicine
POINT
Zdroj: Biomicrofluidics
Popis: Paper-based devices have a wide range of applications in point-of-care diagnostics, environmental analysis, and food monitoring. Paper-based devices can be deployed to resource-limited countries and remote settings in developed countries. Paper-based point-of-care devices can provide access to diagnostic assays without significant user training to perform the tests accurately and timely. The market penetration of paper-based assays requires decreased device fabrication costs, including larger packing density of assays (i.e., closely packed features) and minimization of assay reagents. In this review, we discuss fabrication methods that allow for increasing packing density and generating closely packed features in paper-based devices. To ensure that the paper-based device is low-cost, advanced fabrication methods have been developed for the mass production of closely packed assays. These emerging methods will enable minimizing the volume of required samples (e.g., liquid biopsies) and reagents in paper-based microfluidic devices.
Databáze: OpenAIRE
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