Diaphragma sellae: a surgical reference for transsphenoidal resection of pituitary macroadenomas
| Autor: | Norma Aréchiga, Elisa Nishimura, Moisés Mercado, Gerardo Guinto Balanzar, Miguel Abdo, Patricia Guinto |
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| Rok vydání: | 2010 |
| Předmět: |
Adenoma
Adult Male medicine.medical_specialty Pathology Neoplasm Residual medicine.medical_treatment Neurosurgical Procedures Young Adult Cerebrospinal fluid Postoperative Complications Risk Factors Sphenoid Bone medicine Humans Pituitary Neoplasms Sella Turcica Aged Pituitary stalk Transsphenoidal surgery Diaphragma sellae medicine.diagnostic_test Cerebrospinal fluid leak business.industry Magnetic resonance imaging Middle Aged Reference Standards medicine.disease Magnetic Resonance Imaging Sella turcica medicine.anatomical_structure Pituitary Gland Diabetes insipidus Surgery Female Neurology (clinical) Radiology Dura Mater business |
| Zdroj: | World neurosurgery. 75(2) |
| ISSN: | 1878-8769 |
| Popis: | Objective To classify patterns of descent of the diaphragma sellae (DS) to the sella turcica after transsphenoidal resection of pituitary macroadenomas and to determine whether there is any correlation between type of descent and volume or growth pattern of the tumor, as well as the presence of any postoperative hormone alteration, cerebrospinal fluid leak, and/or residual tumor. Methods One hundred patients with pituitary macroadenomas in which microsurgical transsphenoidal approach was indicated were prospectively included. We classified patterns of descent of the DS into four types: type A: symmetrical descent with a central fold corresponding to the pituitary stalk; type B: asymmetrical with a lateralized fold; type C: symmetrical and uniform descent without any fold; and type D: minimal or no descent in absence of visible residual tumor. A correlation was made between these types of descent and clinical and radiological findings. Results The largest tumors were types A and B; endocrine deficit was more frequent in types A and C, whereas the possibility of residual tumor was more elevated in types B and D. No statistically significant differences were found regarding tumor morphology and cerebrospinal fluid leakage. Conclusions Our results suggest that pattern of descent of the DS may serve as a reference to determine the risk of leaving residual tumor as well as the possibility of developing postoperative endocrine deficit. It is apparent that tumor volume, more than morphology, is the main factor determining type of descent of the DS. |
| Databáze: | OpenAIRE |
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