High Prevalence of Intestinal Pathogens in Indigenous in Colombia
| Autor: | Miriam Hanke, Gustavo Andrés Concha Mendoza, Jessica Hansen, Simone Kann, Cielo Leonor Armenta Quintero, Daniela Bruennert, Ralf Matthias Hagen, José José Crespo Gonzalez, Joy Backhaus, Hagen Frickmann |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Trichuris
030231 tropical medicine helminthes lcsh:Medicine medicine.disease_cause Campylobacter jejuni Cyclospora cayetanensis Necator americanus Article Microbiology 03 medical and health sciences 0302 clinical medicine parasitic diseases medicine protozoa infections Helminths Shigella ddc:610 0303 health sciences biology 030306 microbiology business.industry lcsh:R General Medicine biology.organism_classification Ancylostoma bacterial infections Ascaris lumbricoides business gastrointestinal infection |
| Zdroj: | Journal of Clinical Medicine, Vol 9, Iss 2786, p 2786 (2020) Journal of Clinical Medicine Volume 9 Issue 9 |
| ISSN: | 2077-0383 |
| Popis: | Background: Intestinal infections remain a major public health burden in developing countries. Due to social, ecological, environmental, and cultural conditions, Indigenous peoples in Colombia are at particularly high risk. Materials: 137 stool samples were analyzed by microscopy and real-time-Polymerase Chain Reaction (RT-PCR), targeting protozoan parasites (Giardia intestinalis, Entamoeba histolytica, Cryptosporidium spp., and Cyclospora cayetanensis), bacteria (Campylobacter jejuni, Salmonella spp., Shigella ssp./enteroinvasive E. coli (EIEC), Yersinia spp., enterohemorrhagic E. coli (EHEC), enteropathogenic E. coli ( EPEC), enterotoxin-producing E. coli (ETEC), enteroaggregative E. coli (EAEC), and Tropheryma whipplei), and helminths (Necator americanus, Strongyloides stercoralis, Ascaris lumbricoides, Ancylostoma spp., Trichuris. trichiura, Taenia spp., Hymenolepis nana, Enterobius vermicularis, and Schistosoma spp.). Microscopy found additional cases of helminth infections. Results: At least one pathogen was detected in 93% of the samples. The overall results revealed protozoa in 79%, helminths in 69%, and bacteria in 41%. G. intestinalis (48%), Necator/hookworm (27%), and EAEC (68%) were the most common in each group. Noteworthy, T. whipplei was positive in 7% and T. trichirua in 23% of the samples. A significant association of one infection promoting the other was determined for G. intestinalis and C. jejuni, helminth infections, and EIEC. Conclusions: The results illustrate the high burden of gastrointestinal pathogens among Indigenous peoples compared to other developing countries. Countermeasures are urgently required. |
| Databáze: | OpenAIRE |
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