Histopathology and Immunofluorescent Immunoglobulins in Asthmatics With Aspirin Idiosyncrasy
| Autor: | Gerald M. English, Richard S. Farr, Sheldon L. Spector, Ronald I. Carr |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Fluorescent Antibody Technique Immunoglobulins Inflammation Immunoglobulin E Immunoglobulin D Giemsa stain Fibrin Drug Hypersensitivity Nasal Polyps medicine Humans Sinusitis Basement membrane Aspirin biology business.industry Syndrome General Medicine Middle Aged Asthma medicine.anatomical_structure Otorhinolaryngology Immunology biology.protein Female Surgery Histopathology medicine.symptom Antibody business |
| Zdroj: | Archives of Otolaryngology - Head and Neck Surgery. 113:377-379 |
| ISSN: | 0886-4470 |
| Popis: | • Nearly 700 specimens of polyps and sinus tissues from 12 patients with asthma and aspirin idiosyncrasy were studied with histochemical and immunofluorescent immunoglobulin techniques. Hematoxylin-eosin, Giemsa, and Wright's stains were used for the histochemical analyses. Immunofluorescent antibodies for IgG, IgA, IgM, IgE, IgD, anti-C3, albumin, and fibrin were used. There was a uniform inflammatory reaction in all the tissues. A thick basement membrane and epithelial changes were also present. Immunofluorescent immunoglobulins were consistent in quantity and location in these tissues. IgG, IgA, and IgM were associated with inflammation. IgE was present in all the specimens, but this does not necessarily indicate a reagin-mediated reaction. Anti-C3 excluded the possibility of a hereditary absence of C1 esterase inhibitor. ( Arch Otolaryngol Head Neck Surg 1987;113:377-379) |
| Databáze: | OpenAIRE |
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