Genital warts in Burmeister's porpoises: characterization of Phocoena spinipinnis papillomavirus type 1 (PsPV-1) and evidence for a second, distantly related PsPV

Autor: Christian Desaintes, Joanna Alfaro-Shigueto, Marc Van Ranst, Gérard Orth, Marie-Françoise Van Bressem, Patricia Cassonnet, Koen Van Waerebeek, Annabel Rector
Přispěvatelé: Cetean Conservation Medicine Group (CMED), Cetacean Conservation Medicine Group-CEPEC/Museo de Delfines, Département de Virologie - Department of Virology, Institut Pasteur [Paris], Laboratory of Clinical and Epidemiological Virology, Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven)-Rega Institute for medical research, Nuclear Research Centre, Centre d'Etude de l'Energie Nucléaire (SCK-CEN), Asociacion ProDelphinus, Institut Pasteur [Paris] (IP)
Jazyk: angličtina
Rok vydání: 2007
Předmět:
viruses
MESH: Amino Acid Sequence
MESH: Base Sequence
Genome
Genital warts
0403 veterinary science
Monophyly
MESH: Papillomaviridae
Genus
Phocoena
MESH: Animals
MESH: Phylogeny
Papillomaviridae
Phylogeny
MESH: Evolution
Molecular
Bovine papillomavirus
0303 health sciences
Phylogenetic tree
biology
04 agricultural and veterinary sciences
MESH: Cattle
Condylomata Acuminata
[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology
040301 veterinary sciences
Molecular Sequence Data
Evolution
Molecular
03 medical and health sciences
Open Reading Frames
Viral Proteins
Species Specificity
Virology
medicine
Animals
Humans
MESH: Species Specificity
Amino Acid Sequence
Gene
030304 developmental biology
MESH: Humans
MESH: Molecular Sequence Data
Base Sequence
MESH: Open Reading Frames
medicine.disease
biology.organism_classification
MESH: Viral Proteins
MESH: DNA
Viral
Open reading frame
DNA
Viral
Cattle
MESH: Phocoena
MESH: Condylomata Acuminata
Zdroj: Journal of General Virology
Journal of General Virology, Microbiology Society, 2007, 88 (Pt 7), pp.1928-33. ⟨10.1099/vir.0.82694-0⟩
Journal of General Virology, 2007, 88 (Pt 7), pp.1928-33. ⟨10.1099/vir.0.82694-0⟩
ISSN: 0022-1317
1465-2099
DOI: 10.1099/vir.0.82694-0⟩
Popis: We identified sequences from two distantly related papillomaviruses in genital warts from two Burmeister's porpoises, including a PV antigen-positive specimen, and characterized Phocoena spinipinnis papillomavirus type 1 (PsPV-1). The PsPV-1 genome comprises 7879 nt and presents unusual features. It lacks an E7, an E8 and a bona fide E5 open reading frame (ORF) and has a large E6 ORF. PsPV-1 L1 ORF showed the highest percentage of nucleotide identity (54–55 %) with human papillomavirus type 5, bovine papillomavirus type 3 (BPV-3) and Tursiops truncatus papillomavirus type 2 (TtPV-2). This warrants the classification of PsPV-1 as the prototype of the genus Omikronpapillomavirus. PsPV-1 clustered with TtPV-2 in the E6 and E1E2 phylogenetic trees and with TtPV-2 and BPV-3 in the L2L1 tree. This supports the hypothesis that PV evolution may not be monophyletic across all genes.
Databáze: OpenAIRE
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