A WAO — ARIA — GA2LEN consensus document on molecular-based allergy diagnosis (PAMD@): Update 2020

Autor: John Oppenheimer, Ignacio J. Ansotegui, Mario Morais Almeida, Enrico Scala, Lindo Cox, Michael Levin, Jonathan A. Bernstein, Torsten Zuberbier, Ruby Pawankar, Luciana Kase Tanno, Peter Schmid-Grendelmeier, Nelson Augusto Rosário Filho, Giovanni Melioli, Marianne van Hage, Giorgio Walter Canonica, Thilo Jakob, Rudolf Valenta, Bryan Martin, Juan Carlos Sisul, Carlos Nunes, Philip W. Rouadi, Pedro Giavina Bianchi, Jean Bousquet, Mimi L.K. Tang, José Antonio Ortega Martell, Harald Renz, Lars K. Poulsen, Luis Caraballo, Giovanni Passalacqua, Eleonora Savi, Hugh A. Sampson, Paolo Maria Matricardi, Sandra Nora González Díaz, Alessia Ruiba, Pascal Demoly, Gianenrico Senna, Gary W.K. Wong, Olga Luengo, Victoria Cardona, Riccardo Asero, Jörg Kleine-Tebbe, Motohiro Ebisawa, Mario Sanchez Borges, Olga Patricia Monge Ortega, Erika Jensen-Jarolim, Elisa Villa, Fatima Ferreira, Anahí Yáñez, R. Maximiliano Gómez
Přispěvatelé: Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Sorbonne Université (SU), Hôpital Arnaud de Villeneuve [CHRU Montpellier], Universidade de São Paulo (USP), R Valenta discloses research grants from Viravaxx, Vienna, Austria and serves as a consultant for this company. E Jensen-Jarolim discloses she is a shareholder and inventor on EP 2894478, with Biomedical International R + D GmbH Vienna, has received a grant and lecture honoraria from Bencard GmbH Germany, has received lecture honoraria from Sanofi GmbH, Roxall, Meda, and Novartis, and is a joint Editor-in-Chief of this journal. All other authors have declared they have no competing interests related to this work., The authors extend their appreciation to Naomi Ruff, PhD, for her contribution as editor of the document. The World Allergy Organization thanks Thermo Fisher Scientific for supporting this project, in part, by a medical educational grant. The supporter did not participate in document development.
Rok vydání: 2020
Předmět:
Zdroj: World Allergy Organization Journal, Vol 13, Iss 2, Pp-(2020)
World Allergy Organization Journal
World Allergy Organization Journal, BMC, 2020, 13 (2), pp.100091. ⟨10.1016/j.waojou.2019.100091⟩
The World Allergy Organization Journal
ISSN: 1939-4551
DOI: 10.1016/j.waojou.2019.100091
Popis: Precision allergy molecular diagnostic applications (PAMD@) is increasingly entering routine care. Currently, more than 130 allergenic molecules from more than 50 allergy sources are commercially available for in vitro specific immunoglobulin E (sIgE) testing. Since the last publication of this consensus document, a great deal of new information has become available regarding this topic, with over 100 publications in the last year alone. It thus seems quite reasonable to publish an update. It is imperative that clinicians and immunologists specifically trained in allergology keep abreast of the new and rapidly evolving evidence available for PAMD@.PAMD@ may initially appear complex to interpret; however, with increasing experience, the information gained provides relevant information for the allergist. This is especially true for food allergy, Hymenoptera allergy, and for the selection of allergen immunotherapy. Nevertheless, all sIgE tests, including PAMD@, should be evaluated within the framework of a patient's clinical history, because allergen sensitization does not necessarily imply clinical relevant allergies. Keywords: Diagnosis, Molecular allergy, Cross reactivity, Panallergen, Specific IgE, PAMD@
Databáze: OpenAIRE
Externí odkaz: