The Effect of Hydroalcoholic Extract of Tamarix dioica Flower on Thioacetamide - Induced Histomorphological Changes in Rats
| Autor: | Sedighe Esmaeelzadeh Behabadi, Mehdi Rasekh, Mohammad Reza Hajinezhad, Mohammad Ebrahim َAkbari, Abbas Jamshidian |
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| Jazyk: | perština |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, Vol 13, Iss 12, Pp 65-74 (2020) |
| ISSN: | 2008-1375 1735-7799 |
| Popis: | Background and Objectives: The present experimental study was aimed to investigate the effect of T. dioica flower hydroalcoholic extract on thioacetamide induced histopathological changes. Methods: Thirty adult male Wistar rats, were randomly divided into three groups of control (normal saline); negative control (thioacetamide 50 mg/kg) and group that received thioacetamide and T. dioica flower extract (200 mg/kg). The third group received the T. dioica flowers extract two weeks before the injection of thioacetamide and two weeks after the injection of thioacetamide. The healthy control group and the negative control group received normal saline. At the end of the experiment, blood samples, were obtained from the heart to determine lever enzymes aspartate aminotransferase (AST), alanine aminotransaminase (ALT), blood urea nitrogen (BUN), and creatinine. After euthanasia, tissue samples, were examined using a light microscope after staining with haematoxylin-eosin. Data were analyzed by one-way ANOVA statistical test. Statistical significance was considered as p |
| Databáze: | OpenAIRE |
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