Cross hepatotoxicity between tricyclic antidepressants
| Autor: | Dominique Larrey, Jean-Pierre Benhamou, Bernard Rueff, M Algard, Dominique Pessayre, Danan G, Jean Geneve |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Adult
Clomipramine medicine.drug_class Amineptine Tricyclic antidepressant Dibenzocycloheptenes Antidepressive Agents Tricyclic Pharmacology Humans Medicine Drug Interactions chemistry.chemical_classification business.industry Gastroenterology chemistry Acute Disease Toxicity Female Chemical and Drug Induced Liver Injury business Research Article Tricyclic medicine.drug Acute hepatitis |
| Zdroj: | Gut. 27:726-727 |
| ISSN: | 0017-5749 |
| DOI: | 10.1136/gut.27.6.726 |
| Popis: | Cross hepatotoxicity between drugs in very uncommon. We report the case of a patient in whom acute hepatitis was induced by a tricyclic antidepressant, amineptine, and recurred early after administration of another tricyclic antidepressant, clomipramine. This observation suggests that the tricyclic ring is involved in the mechanism of the deleterious effect of both drugs to the liver. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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