Incidence and Predictors of Left Atrial Appendage Thrombus in Patients Treated With Nonvitamin K Oral Anticoagulants Versus Warfarin Before Catheter Ablation for Atrial Fibrillation
| Autor: | Joanne Wyrembak, Benjamin A. Steinberg, Tristram D. Bahnson, Zainab Samad, Brett D. Atwater, Kristen Bova Campbell, James P. Daubert, Eric J. Velazquez |
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| Rok vydání: | 2017 |
| Předmět: |
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medicine.medical_specialty medicine.medical_treatment Contrast Media Catheter ablation 030204 cardiovascular system & hematology Risk Assessment 03 medical and health sciences 0302 clinical medicine Left atrial Internal medicine Humans Medicine Atrial Appendage cardiovascular diseases 030212 general & internal medicine Thrombus Aged Retrospective Studies business.industry Incidence Incidence (epidemiology) Warfarin Anticoagulants Thrombosis Atrial fibrillation Retrospective cohort study Middle Aged medicine.disease Ablation Surgery Catheter Ablation Cardiology Female Cardiology and Cardiovascular Medicine business human activities Echocardiography Transesophageal Factor Xa Inhibitors medicine.drug |
| Zdroj: | The American Journal of Cardiology. 119:1017-1022 |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/j.amjcard.2016.12.008 |
| Popis: | The utility of routine transesophageal echocardiography (TEE) to exclude left atrial appendage (LAA) thrombus before atrial fibrillation (AF) ablation in patients treated with nonvitamin K oral anticoagulant (NOAC) therapy is unclear. This single-center retrospective study sought to investigate the incidence of LAA thrombus in patients undergoing routine TEE before AF ablation treated with warfarin or NOAC therapy. We included 937 routine pre-AF ablation TEE procedures performed in patients treated with warfarin (n = 517) or NOAC (n = 420). Patients were anticoagulated without interruption for at least 4 consecutive weeks before the TEE. Patients treated with warfarin had lower LAA velocity and underwent TEE earlier in the study period than those treated with NOAC (p 0.05). The incidence of LAA thrombus was higher in patients treated with warfarin (1.55%, 8 of 517) compared with patients treated with NOAC (0.24%, 1 of 420, p = 0.0473 for difference). No LAA thrombus was identified in NOAC-treated patients with a CHA |
| Databáze: | OpenAIRE |
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