A Comparison Between Bearing and Non-bearing Human Bone: Mechanical Testing and Micro-Architecture Assessment
| Autor: | Hervé Morvan, Christian Fontaine, Rémi Delille, Eric Markiewicz, Xavier Roothaer |
|---|---|
| Přispěvatelé: | Laboratoire d'Automatique, de Mécanique et d'Informatique industrielles et Humaines - UMR 8201 (LAMIH), Centre National de la Recherche Scientifique (CNRS)-Université Polytechnique Hauts-de-France (UPHF)-INSA Institut National des Sciences Appliquées Hauts-de-France (INSA Hauts-De-France), Université Lille 2 - Faculté de Médecine, Université de Valenciennes et du Hainaut-Cambrésis (UVHC)-Centre National de la Recherche Scientifique (CNRS)-INSA Institut National des Sciences Appliquées Hauts-de-France (INSA Hauts-De-France) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Materials science
Long bone 030209 endocrinology & metabolism law.invention Bone remodeling 03 medical and health sciences 0302 clinical medicine law medicine Process (anatomy) ComputingMilieux_MISCELLANEOUS 030304 developmental biology 0303 health sciences Bearing (mechanical) [SPI.MECA]Engineering Sciences [physics]/Mechanics [physics.med-ph] Skeleton (computer programming) Diaphysis medicine.anatomical_structure Cortical bone Cadaveric spasm Biomedical engineering |
| Zdroj: | Mechanics of Biological Systems and Materials & Micro-and Nanomechanics Mechanics of Biological Systems and Materials & Micro-and Nanomechanics, 4, Springer International Publishing, pp.49-56, 2020, Conference Proceedings of the Society for Experimental Mechanics Series, ⟨10.1007/978-3-030-30013-5_9⟩ Society for Experimental Mechanics-SEM 2019 Society for Experimental Mechanics-SEM 2019, Jun 2019, Reno, United States Mechanics of Biological Systems and Materials & Micro-and Nanomechanics, Volume 4 ISBN: 9783030300128 |
| Popis: | International audience; An adult skeleton has over 200 bones. Each bone has a specific function. These different functions bring different types of mechanical loadings. To ensure a healthy behavior of the bone, a throughout life process occurs on the micro-architecture of the cortical bone. This process highly depends on the stress applied on the bone. The micro-architecture is able to supply blood and nutrients into the bone matrix and acts on the bone remodeling process. The architecture is formed by vascular canals where the orientation depends on the main axis of the mechanical loading. Vascular canals of the cortical bone located in long bone diaphysis are mainly oriented along the longitudinal axis of the diaphysis. Moreover, the canal network is tortuous and several geometrical features should affect the macroscopic behavior of the bone. The novelty of this work is to use a method which accurately describes the vascular architecture of the cortical bone based on micro-computed tomography and to correlate these results with the macroscopic mechanical behavior of the cortical bone. This experimental study is based on the extraction of cortical bone samples from four cadaveric human subjects. For each human subject, left and right humeri and femurs are studied. Dumbbell-shaped bone specimens are prepared from each bone. Care was taken to preserve bone properties after extraction: a maximum of 15 days was fixed between the extraction and the mechanical testing. Samples were constantly kept hydrated and stored at 4 °C in order to avoid frost/defrost cycles. Specimens are scanned and subsequently mechanically loaded to failure. Results will show the impact of the laterality of the bone on the architecture, the impact of loading on the bone on the architecture by comparing humeral and femoral samples for each human subject and finally the impact of the architecture on the mechanical behavior of the bone. |
| Databáze: | OpenAIRE |
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