Segmental intracellular, interstitial, and intravascular volume changes during simulated hemorrhage and resuscitation: A case study
| Autor: | Julian M. Stewart, Richard W. Montgomery, Leslie D. Montgomery, Marty Loughry, Michael Bodo, Wayne A. Gerth |
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| Rok vydání: | 2019 |
| Předmět: |
Resuscitation
Bioimpedance resuscitation 0206 medical engineering 030232 urology & nephrology Biomedical Engineering Biophysics Hemodynamics 02 engineering and technology Blood flow 020601 biomedical engineering 03 medical and health sciences 0302 clinical medicine Extracellular fluid compartment volumes Extracellular Intravascular volume status Plethysmograph hemorrhage Compartment (pharmacokinetics) Research Articles Biomedical engineering |
| Zdroj: | Journal of Electrical Bioimpedance |
| ISSN: | 1891-5469 |
| DOI: | 10.2478/joeb-2019-0006 |
| Popis: | This paper describes a new combined impedance plethysmographic (IPG) and electrical bioimpedance spectroscopic (BIS) instrument and software that will allow noninvasive real-time measurement of segmental blood flow, intracellular, interstitial, and intravascular volume changes during various fluid management procedures. The impedance device can be operated either as a fixed frequency IPG for the quantification of segmental blood flow and hemodynamics or as a multi-frequency BIS for the recording of intracellular and extracellular resistances at 40 discrete input frequencies. The extracellular volume is then deconvoluted to obtain its intravascular and interstitial component volumes as functions of elapsed time. The purpose of this paper is to describe this instrumentation and to demonstrate the information that can be obtained by using it to monitor segmental compartment volume responses of a pig model during simulated hemorrhage and resuscitation. Such information may prove valuable in the diagnosis and management of rapid changes in the body fluid balance and various clinical treatments. |
| Databáze: | OpenAIRE |
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