Meckel's Cave and Somatotopy of the Trigeminal Ganglion
| Autor: | Ming Zhang, Zhaoyang Xu, Han Zhang, Jacob D. Bond |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Neurosurgical Procedures
03 medical and health sciences Trigeminal ganglion 0302 clinical medicine Trigeminal neuralgia medicine Humans business.industry Neural crest Somatotopic arrangement Anatomy Trigeminal Neuralgia Positive patient medicine.disease Ganglion medicine.anatomical_structure Cranial Fossa Posterior Trigeminal Ganglion 030220 oncology & carcinogenesis Embryology Surgery Neurology (clinical) Dura Mater Meckel's cave business 030217 neurology & neurosurgery |
| Zdroj: | World neurosurgery. 148 |
| ISSN: | 1878-8769 |
| Popis: | Background The anatomy and spatial relationships of the dural sac comprising the Meckel cave (MC) and its ensheathed trigeminal ganglion (TG) are exceedingly intricate and complex. There are conflicting accounts in the literature regarding the dural configuration of the MC around the ganglion and the dual embryology of the MC and TG is still unclear. Methods A combined systematic and narrative literature review was conducted to collate articles addressing MC and TG anatomy, in addition to their embryology, role in tumor spread, somatotopy, and association with trigeminal neuralgia. Results Three key anatomic models by Paturet (1964), Lazorthes (1973), and Lang and Ferner (1983) have been put forward to show the arrangement of the MC around the TG. The TG is formed from both neural crest and placodal cells and drags the enveloping dura caudally to form the MC prolongation during development. Both a mediolateral and dorsoventral somatotopic arrangement of neurons exists in the TG, which corresponds to the 3 nerve divisions, of which V2 and V3 are prone to perineural tumor spread along their course. Conclusions Sound knowledge concerning the dural arrangement of the MC and the trigeminal divisions will be invaluable in optimally treating cancers in this region, and understanding TG somatotopy will immensely improve treatment of trigeminal neuralgia in terms of specificity, efficacy, and positive patient outcomes. |
| Databáze: | OpenAIRE |
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