Safety assessment of fermented jackfruit ( Artocarpus heterophyllus ) pulp and leaves in Sprague‐Dawley rats
Autor: | Shaiful Adzni Sharifudin, Sarah Sabidi, Shazwan Abd Shukor, Soo Peng Koh, Yun Shin Sew |
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Rok vydání: | 2020 |
Předmět: |
medicine.medical_specialty
030309 nutrition & dietetics lcsh:TX341-641 engineering.material jackfruit leaves 03 medical and health sciences Artocarpus 0404 agricultural biotechnology Lower body Oral administration medicine Sprague dawley rats Sprague‐Dawley rats fermentation Original Research 0303 health sciences Traditional medicine biology Pulp (paper) toxicity jackfruit pulp 04 agricultural and veterinary sciences biology.organism_classification 040401 food science Toxicity engineering Histopathology Fermentation lcsh:Nutrition. Foods and food supply Food Science |
Zdroj: | Food Science & Nutrition Food Science & Nutrition, Vol 8, Iss 8, Pp 4370-4378 (2020) |
ISSN: | 2048-7177 |
Popis: | Fermented jackfruit (Artocarpus heterophyllus) extracts were produced using pure symbiotic culture of bacteria and yeast (SCOBY) under controlled fermentation process. Both female and male Sprague‐Dawley rats were orally administrated with 4,000 mg/kg of fermented jackfruit pulp and leaves extracts for 28 consecutive days. Body weight of rats was recorded at 1‐week interval until necropsy day. There was no mortality reported along the experiment with no significant differences (p > .05) record among organ histopathology and blood biochemical parameters in treated groups when compared to control group. Interestingly, there were significant differences (p No toxicity symptoms were observed in Sprague‐Dawley rats for both sexes after 28 days oral administration with fermented jackfruit pulp and leaves. There were significant differences (p |
Databáze: | OpenAIRE |
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