Aspects of Point-of-Care Diagnostics for Personalized Health Wellness
| Autor: | Sakina Khurana, Ajeet Kaushik, Neeraj Dilbaghi, Vanish Kumar, Monika Nehra, Ki-Hyun Kim, Sandeep Kumar |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Computer science
Point-of-care testing Biophysics microfluidics Pharmaceutical Science Bioengineering Personalized health 02 engineering and technology Review 010402 general chemistry Diagnostic system infectious diseases Communicable Diseases 01 natural sciences Biomaterials Infectious disease diagnosis Lab-On-A-Chip Devices Drug Discovery Humans Precision Medicine Scope (project management) Organic Chemistry General Medicine Research opportunities 021001 nanoscience & nanotechnology Precision medicine lateral flow strips 0104 chemical sciences Risk analysis (engineering) Point-of-Care Testing Interdigitated electrode Smartphone 0210 nano-technology point-of-care devices |
| Zdroj: | International Journal of Nanomedicine |
| ISSN: | 1178-2013 1176-9114 |
| Popis: | Advancements in analytical diagnostic systems for point-of-care (POC) application have gained considerable attention because of their rapid operation at the site required to manage severe diseases, even in a personalized manner. The POC diagnostic devices offer easy operation, fast analytical outcome, and affordable cost, which promote their advanced research and versatile adoptability. Keeping advantages in view, considerable efforts are being made to design and develop smart sensing components such as miniaturized transduction, interdigitated electrodes-based sensing chips, selective detection at low level, portable packaging, and sustainable durability to promote POC diagnostics according to the needs of patient care. Such effective diagnostics systems are in demand, which creates the challenge to make them more efficient in every aspect to generate a desired bio-informatic needed for better health access and management. Keeping advantages and scope in view, this mini review focuses on practical scenarios associated with miniaturized analytical diagnostic devices at POC application for targeted disease diagnostics smartly and efficiently. Moreover, advancements in technologies, such as smartphone-based operation, paper-based sensing assays, and lab-on-a-chip (LOC) which made POC more sensitive, informative, and suitable for major infectious disease diagnosis, are the main focus here. Besides, POC diagnostics based on automated patient sample integration with a sensing platform is continuously improving therapeutics interventions against specific infectious disease. This review also discussed challenges associated with state-of-the-art technology along with future research opportunities to design and develop next generation POC diagnostic systems needed to manage infectious diseases in a personalized manner. |
| Databáze: | OpenAIRE |
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