Causative bacteria associated with a clinically relevant postoperative pancreatic fistula infection after distal pancreatectomy

Autor: Yuichi Hosokawa, Yuichi Nagakawa, Shingo Kozono, Tomoki Shirota, Hitoe Nishino, Naoya Nakagawa, Kenta Suzuki, Chie Takishita, Kenji Katsumata, Tetsuo Ishizaki, Akihiko Tsuchida, Masanori Akashi, Hiroaki Osakabe
Rok vydání: 2021
Předmět:
Zdroj: Surgery today. 51(11)
ISSN: 1436-2813
Popis: Clinically relevant postoperative pancreatic fistulas (CR-POPF) occurring after distal pancreatectomy often cause intra-abdominal infections. We monitored the presence of bacterial contamination in the ascitic fluid after distal pancreatectomy to clarify the bacterial origin of intra-abdominal infections associated with CR-POPF. In 176 patients who underwent distal pancreatectomy, ascitic fluid bacterial cultures were performed on postoperative days (POD) 1–4 and when the drainage fluid became turbid. The association between postoperative ascitic bacterial contamination and CR-POPF incidence was investigated. CR-POPF occurred in 18 cases (10.2%). Among the patients with CR-POPF, bacterial contamination was detected in 0% on POD 1, in 38.9% on POD 4, and in 72.2% on the day (median, day 9.5) when the drainage fluid became turbid. A univariate analysis revealed a significant difference in ascitic bacterial contamination on POD 4 (p
Databáze: OpenAIRE