Comparative study of cefoperazone and spectinomycin for treatment of uncomplicated gonorrhea in men
| Autor: | Franklyn N. Judson, H. Hunter Handsfield, Josephine M. Ehret, Michael Verdon, Edward W. Hook |
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| Jazyk: | angličtina |
| Rok vydání: | 1986 |
| Předmět: |
Neisseria gonorrhoeae Infections
Adult Male medicine.medical_specialty Spectinomycin Adolescent medicine.drug_class Antibiotics Cephalosporin Gonorrhea Cefoperazone Chlamydia trachomatis Microbial Sensitivity Tests medicine.disease_cause urologic and male genital diseases Gastroenterology Spectinomycine Random Allocation Internal medicine Medicine Humans Pharmacology (medical) Pharmacology Gynecology business.industry Chlamydia Infections medicine.disease female genital diseases and pregnancy complications Infectious Diseases business medicine.drug Research Article |
| Popis: | Beta-lactamase-negative Neisseria gonorrhoeae infections were treated with single-dose cefoperazone (0.5 or 1.0 g) or spectinomycin (2.0 g). Anogenital infections were cured in 36 (83%) of 43 volunteers given 0.5 g of cefoperazone, 61 of 61 volunteers given 1.0 g of cefoperazone, and 99 of 100 volunteers given spectinomycin. The cefoperazone geometric mean MIC for 242 isolates was 0.028 microgram/ml. Cefoperazone (1.0 g) and spectinomycin (2.0 g) are comparable for the therapy of anogenital gonorrhea in men. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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