D2 vs D2 plus para-aortic lymph node dissection for advanced gastric cancer
| Autor: | Necdet Ozalp, Mehmet Mahir Özmen, Munevver Moran, Selda Seckin, Fusun Ozmen, Baris Zulfikaroglu |
|---|---|
| Přispěvatelé: | İstinye Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Ozmen, Mehmet Mahir |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Prognostic variable medicine.medical_treatment Malignancy 03 medical and health sciences 0302 clinical medicine Gastrectomy medicine Risk-Factors Stage (cooking) Mortality D2 Lymphadenectomy Lymph node Survival Benefit business.industry Cancer Lymphadenectomy Prognosis Extended D2 medicine.disease D2 Lymphadenectomy Plus Para-Aortic Lymph Node Dissection Western Patients Surgery Dissection medicine.anatomical_structure D-2 Resections 030220 oncology & carcinogenesis Advanced Gastric Cancer Surgical-Treatment Original Article 030211 gastroenterology & hepatology Morbidity business D3 |
| Zdroj: | Turk J Surg |
| Popis: | Objective: Gastric cancer is a common malignancy worldwide. Effective treatment by interdisciplinary cooperation is important, and surgery still plays an important role. Material and Methods: In a ten-year period, 355 patients were diagnosed to have gastric cancer. One hundred and sixty-two patients with a median (range) age of 58 (23-83) years were eligible for the study. There were 107 patients in D2 and 55 patients in D2 lymphadenectomy plus para-aortic lymph node (PALN) dissection group. The two groups were compared in terms of complications, morbidity, mortality and long-term survival. Results: Length of stay was 12 (8-34) days for D2 and 14 (8-42) days for D2 plus PALND. Total number of operative mortality was 8/162 (5%), and it was not different between the groups. Twenty patients (18%) had complications in D2 group and 9 (17%) patients in D2 plus PALND group. Overall survival was also similar between the groups, but patients with T3-T4 tumors, patients with stage IIIA and IIIB disease had better survival with D2 plus PALN dissection. We found that the depth of invasion, PLN, ratio (PLN/TLN), stage and LND were all prognostic variables. Conclusion: This study showed that D2 plus PALN dissection for advanced gastric cancer can be performed as safely as a standard D2 dissection by experienced surgeons without increasing postoperative morbidity and mortality. D2 plus PALN dissection should be preferred in the advanced stage of the disease (IIIA-IIIB) as it increases the rate of survival. |
| Databáze: | OpenAIRE |
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