Combination Angiotensin Receptor Blocker/Hydrochlorothiazide as Initial Therapy in the Treatment of Patients With Severe Hypertension
| Autor: | Christina M. Salerno, Robin Mukherjee, Alan H. Gradman, Laura A. Demopoulos |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Adult
Male medicine.medical_specialty Angiotensin receptor Sodium Chloride Symporter Inhibitors Endocrinology Diabetes and Metabolism medicine.medical_treatment Urology Losartan Hydrochlorothiazide Internal medicine Internal Medicine medicine Humans Prospective Studies Diuretics Thiazide Aged Aged 80 and over business.industry Middle Aged Original Papers Regimen Treatment Outcome Endocrinology Blood pressure Tolerability Hypertension Drug Therapy Combination Female Diuretic Cardiology and Cardiovascular Medicine business Angiotensin II Type 1 Receptor Blockers medicine.drug |
| Zdroj: | J Clin Hypertens (Greenwich) |
| ISSN: | 1751-7176 1524-6175 |
| DOI: | 10.1111/j.1524-6175.2004.03808.x |
| Popis: | Patients with severe hypertension are at high risk for cardiovascular events. The authors hypothesized that initial treatment with a combination angiotensin receptor blocker/diuretic agent would be safe and more effective than initial treatment with a single agent for these patients. In this 6‐week, double‐blind trial, 585 patients were randomized to losartan/hydrochlorothiazide or losartan as monotherapy and titrated as needed at 2‐week intervals to reach goal blood pressure ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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