Serum Protein Profiles in Carcinoma of the Kidney
| Autor: | N.B. Pidcock, B. Richards, Edward H. Cooper, M.R.G. Robinson |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Male
Glucose-6-phosphate isomerase alpha 1-Antichymotrypsin Urology Serum protein medicine Carcinoma Chymotrypsin Humans Protease Inhibitors Beta (finance) Kidney Haptoglobins business.industry Glucose-6-Phosphate Isomerase Kidney Carcinoma Acute-phase protein Blood Proteins Orosomucoid medicine.disease Kidney Neoplasms C-Reactive Protein medicine.anatomical_structure alpha 1-Antitrypsin Cancer research Female beta 2-Microglobulin business Kidney cancer |
| Zdroj: | European Urology. 8:32-36 |
| ISSN: | 1873-7560 0302-2838 |
| DOI: | 10.1159/000473474 |
| Popis: | The levels of serum acute phase reactant proteins (APRPs) have been examined in untreated kidney carcinoma and during the evolution of metastases. These proteins can provide a warning of the likelihood of extensive local or metastatic spread at first presentation. The levels of APRPs rise with increasing tumour burden but the system is insensitive to small tumour burdens. beta 2-Microglobulin levels do not contribute additional information. Serum phosphohexose isomerase tends to be elevated when there is a large tumour burden but its change does not accurately mirror the rate of expansion of the tumour. The APRPs and phosphohexose isomerase are useful in alerting the clinician to the probability of metastases or large local masses in kidney cancer, but have a limited use in monitoring. |
| Databáze: | OpenAIRE |
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