Efficacy and safety of transnasal butorphanol for pain relief after anal surgery
| Autor: | Liang-Tsai Wan, Cheng-Wen Hsiao, Chen-Ming Mai, Hsiang-Yu Yang, Chang-Chieh Wu, Yu-Ching Chou, Shu-Wen Jao |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Meperidine Butorphanol Butorphanol Nasal Spray Fistulectomy Pain relief Anal Canal law.invention Postoperative Complications Randomized controlled trial law otorhinolaryngologic diseases Medicine Humans Rectal Fistula Rectal fistula Analgesics Pain Postoperative business.industry Gastroenterology Anal surgery General Medicine Anal canal Length of Stay Middle Aged Surgery Brief Articles medicine.anatomical_structure Treatment Outcome Anesthesia Female Safety business medicine.drug |
| Popis: | To compare the analgesic properties and efficacy of transnasal butorphanol with intramuscular meperidine after anal surgery.Sixty patients who underwent fistulectomy were enrolled in the study from January 2006 to December 2007. They were randomly divided into transnasal butorphanol (n = 30) or intramuscular meperidine (n = 30) treatment groups. Assessment of postoperative pain was made using a visual analogue scale (VAS). The VAS score was recorded 6 h after the completion of surgery, before receiving the first dose of analgesic, 60 min after analgesia and the next morning. Any adverse clinical effects such as somnolence, dizziness, nausea or vomiting were recorded. Satisfaction with narcotic efficacy, desire to use the particular analgesic in the future and any complaints were recorded by patients using questionnaires before being discharged.Forty-two men and eighteen women were included in the study. There were no significant differences in VAS scores between the groups within 24 h. Length of hospital stay and the incidence of adverse effects between the groups were similar. In addition, most patients were satisfied with butorphanol nasal spray and wished to receive this analgesic in the future, if needed.Butorphanol nasal spray is effective for the relief of pain after fistulectomy. However, it offered patients more convenient usage and would be suitable for outpatients. |
| Databáze: | OpenAIRE |
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