Antigenic variability in Trichuris trichiura populations
| Autor: | C. S. Needham, Edward S. Cooper, Donald A. P. Bundy, R. M. Currie, Lesley Drake |
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| Rok vydání: | 1998 |
| Předmět: |
Male
Blotting Western Zoology Biology Statistics Nonparametric Host-Parasite Interactions Sex Factors Antigen Immunity parasitic diseases Antigenic variation Animals Humans Parasite hosting Trichuriasis Child West indies Plasma samples Host (biology) biology.organism_classification Antigenic Variation Trichuris Infectious Diseases Antigens Helminth Immunology Trichuris trichiura Electrophoresis Polyacrylamide Gel Female Animal Science and Zoology Parasitology |
| Zdroj: | Parasitology. 117:347-353 |
| ISSN: | 1469-8161 0031-1820 |
| DOI: | 10.1017/s0031182098003084 |
| Popis: | The present study examines antigenic variability for the human whipworm Trichuris trichiura. Recognition by IgG of somatic antigens of individual worms collected from 3 intensely infected children from Jamaica, West Indies has been investigated by immunoblotting. When probed with 1 plasma sample, significant differences in recognition of 2 selected antigens among worm populations and between male and female worms was observed. In addition, there was evidence for antigenic variability within worm populations at the individual worm level. Such variation may have considerable implications for the development of immunity to parasitic nematodes. |
| Databáze: | OpenAIRE |
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