Association Between Pretreatment Sleep Disturbance and Radiation Therapy-Induced Pain in 573 Women With Breast Cancer
| Autor: | Deborah J. Ossip, Julia E Inglis, Thomas Anderson, Dongmei Li, Anita R. Peoples, Sheila N. Garland, Lisa S. Evans, Vincent Vinciguerra, James L. Wade, Michael L. Perlis, Wilfred R. Pigeon, Gary R. Morrow, Julie Ryan Wolf |
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| Rok vydání: | 2021 |
| Předmět: |
Sleep Wake Disorders
medicine.medical_specialty medicine.medical_treatment Population Pain Breast Neoplasms Context (language use) Article 03 medical and health sciences 0302 clinical medicine Breast cancer Internal medicine Humans Medicine 030212 general & internal medicine education Fatigue Mastectomy General Nursing Depression (differential diagnoses) Sleep disorder education.field_of_study Depression business.industry medicine.disease Radiation therapy Anesthesiology and Pain Medicine 030220 oncology & carcinogenesis Female Neurology (clinical) Sleep business Anxiety disorder |
| Zdroj: | J Pain Symptom Manage |
| ISSN: | 0885-3924 |
| DOI: | 10.1016/j.jpainsymman.2020.07.041 |
| Popis: | CONTEXT: Pain can be a debilitating side effect of radiation therapy (RT). Data from the general population has shown that sleep disturbance can influence pain incidence and severity; however, less is known about this relationship in breast cancer patients receiving RT. OBJECTIVES: This secondary analysis examined the association of pre-treatment moderate/severe levels of sleep disturbance with subsequent RT-induced pain after adjusting for pre-RT pain. METHODS: We report on 573 female breast cancer patients undergoing RT from a previously completed phase II clinical trial for radiation dermatitis. Sleep disturbance, total pain, and pain subdomains – sensory pain, affective pain, and perceived pain intensity were assessed at pre- and post-RT. At pre-RT, patients were dichotomized into 2 groups: those with moderate/severe sleep disturbance (N=85) vs. those with no/mild sleep disturbance (control; N=488). RESULTS: At pre-RT, women with moderate/severe sleep disturbance were younger, less likely to be married, more likely to have had mastectomy and chemotherapy, and more likely to have depression/anxiety disorder and fatigue than the control group (all p’s |
| Databáze: | OpenAIRE |
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