Examination of 2-methacryloyloxyethyl phosphorylcholine polymer coated acrylic resin denture base material: surface characteristics and Candida albicans adhesion
Autor: | Gülçin Akca, A. Dilek Nalbant, İrem Türkcan, Erhan Bat |
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Rok vydání: | 2017 |
Předmět: |
Denture Bases
Materials science Polymers Surface Properties Phosphorylcholine Biomedical Engineering Biophysics Acrylic Resins Bioengineering 02 engineering and technology engineering.material Polymerization Biomaterials Contact angle 03 medical and health sciences 0302 clinical medicine Coating Coated Materials Biocompatible Candida albicans Materials Testing Spectroscopy Fourier Transform Infrared Surface roughness Humans Polymethyl Methacrylate Composite material Acrylic resin chemistry.chemical_classification Stomatitis biology Candidiasis 030206 dentistry Adhesion Polymer 021001 nanoscience & nanotechnology biology.organism_classification chemistry visual_art Biofilms engineering visual_art.visual_art_medium Microscopy Electron Scanning Wettability Methacrylates 0210 nano-technology |
Zdroj: | Journal of materials science. Materials in medicine. 29(7) |
ISSN: | 1573-4838 |
Popis: | The aim of this study is to evaluate the effects of 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer coating with various concentrations onto acrylic resin denture base material on surface characteristics such as contact angle and surface roughness and on Candida albicans adhesion which is the major factor of denture stomatitis. Specimens, prepared from heat-polymerized acrylic denture base material, were divided into control and three test groups, randomly. Surfaces of the specimens in test groups were coated with poly(MPC) (PMPC) by graft polymerization of MPC in different concentrations (0.25 mol/L; 0.50 mol/L and 0.75 mol/L), while no surface treatment was applied to the control group. Contact angles and surface roughness were examined, and chemical composition of the surfaces was analyzed by Attenuated Total Reflectance-Fourier Transform Infrared Spectroscopy (FTIR) to verify the presence of PMPC coatings. Then, specimens were incubated with C. albicans for 18 h and the number of adhered cells was determined. Upon PMPC coating, the contact angle values statistically decreased, but no difference was found in surface roughness values. A statistically significant decrease was observed in C. albicans adhesion in parallel with the increase in the MPC polymer concentration. There was no significant difference between 0.50 mol/L and 0.75 mol/L groups in terms of adhesion. These findings indicated that graft polymerization of MPC on acrylic denture base material reduces the adhesion of C. albicans, and may be evaluated as a coating for prevention of denture stomatitis. |
Databáze: | OpenAIRE |
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