Nodal Peripheral T-cell Lymphoma with T Follicular Helper Phenotype Presenting as Chorea During Treatment: A Case Report and Literature Review
| Autor: | Tadashi Yoshino, Hiroki Takasuka, Keiko Fujii, Hideaki Fujiwara, Nobuharu Fujii, Noboru Asada, Wataru Kitamura, Ken-ichi Matsuoka, Hisakazu Nishimori, Koji Abe, Ryo Sasaki, Daisuke Ennishi, Ryoya Yukawa, Yoshinobu Maeda, Chikamasa Yoshida |
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| Rok vydání: | 2021 |
| Předmět: |
Male
Pathology medicine.medical_specialty single photon-emission computed tomography Case Report 030204 cardiovascular system & hematology Single-photon emission computed tomography 03 medical and health sciences 0302 clinical medicine Follicular phase Internal Medicine medicine Humans chorea Cerebral perfusion pressure peripheral T-cell lymphoma Aged Tomography Emission-Computed Single-Photon medicine.diagnostic_test business.industry Brain Lymphoma T-Cell Peripheral Chorea T-Lymphocytes Helper-Inducer General Medicine Iofetamine medicine.disease Peripheral T-cell lymphoma Lymphoma Peripheral Phenotype Cerebral blood flow Cerebrovascular Circulation 030211 gastroenterology & hepatology Neoplasm Recurrence Local medicine.symptom business |
| Zdroj: | Internal Medicine |
| ISSN: | 1349-7235 0918-2918 |
| DOI: | 10.2169/internalmedicine.7180-21 |
| Popis: | A 72-year-old man presented with chorea while undergoing treatment for recurrence of nodal peripheral T-cell lymphoma with T follicular helper (TFH) phenotype. An examination by brain N-isopropyl-p-iodoamphetamine (I-123-IMP)-single photon emission computed tomography (SPECT) revealed no abnormalities other than a decreased cerebral blood flow (CBF) in the left striatum. After four courses of salvage chemotherapy, his clinical symptoms and asymmetric cerebral perfusion improved, suggesting that the decreased CBF had caused chorea. The significance of brain SPECT has not been fully clarified in patients with chorea-associated malignant lymphoma, warranting further investigations. Brain SPECT is an alternative approach to identify abnormalities in such patients. |
| Databáze: | OpenAIRE |
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