A new experimentally validated formula to calculate the QT interval in the presence of left bundle branch block holds true in the clinical setting
| Autor: | Bernd Lemke, Fuad Hasan, Zana Karosiene, Axel Kloppe, Artak Margkarian, Markus Zarse, Eleni Pechlivanidou, Damir Erkapic, Harilaos Bogossian, Dirk Bandorski, Melchior Seyfarth, Quy Suu Nguyen, Dominik Schultes, Gerrit Frommeyer, Dejan Mijic, Lars Eckardt, Ilias Ninios |
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| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test Transcatheter aortic Bundle branch block business.industry Left bundle branch block Prolongation Original Articles General Medicine 030204 cardiovascular system & hematology medicine.disease QT interval Bundle of His 03 medical and health sciences QRS complex 0302 clinical medicine medicine.anatomical_structure Physiology (medical) Internal medicine Cardiology Medicine 030212 general & internal medicine Cardiology and Cardiovascular Medicine business Electrocardiography |
| Zdroj: | Annals of Noninvasive Electrocardiology. 22:e12393 |
| ISSN: | 1082-720X |
| DOI: | 10.1111/anec.12393 |
| Popis: | Background The evaluation of the QT interval in the presence of left bundle branch block (LBBB) is associated with the challenge to discriminate native QT interval from the prolongation due to the increase in QRS duration. The newest formula to evaluate QT interval in the presence of LBBB suggests: modified QT during LBBB = measured QT interval minus 50% of LBBB duration. The purpose of this study is therefore to validate the abovementioned formula in the clinical setting. Methods Validation in two separate groups of patients: Patients who alternated between narrow QRS and intermittent LBBB and patients with narrow QRS who developed LBBB after transcatheter aortic valve implantation (TAVI). Results The acquired mean native QTc intervals and those calculated by the presented formula displayed no significant differences (p > .99 and p > .75). Conclusions In this study we proved for the first time the validity and applicability of the experimentally acquired formula for the evaluation of the QT interval in the presence of LBBB in a clinical setting. |
| Databáze: | OpenAIRE |
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