Preliminary outcomes after transcatheter aortic valve implantation in patients with systemic sclerosis
| Autor: | Eustachio Agricola, Gennaro Giustino, Ottavio Alfieri, Pietro Spagnolo, Chiara Bernelli, Antonio Colombo, Azeem Latib, Matteo Montorfano, Micaela Cioni, Alaide Chieffo, Vasileios F. Panoulas, Remo Daniel Covello |
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| Přispěvatelé: | Bernelli, C, Chieffo, A, Giustino, G, Montorfano, M, Latib, A, Cioni, M, Panoulas Vasileios, F, Covello, Rd, Agricola, E, Spagnolo, P, Alfieri, Ottavio, Colombo, A. |
| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Sedation Population Scleroderma Cohort Studies Transcatheter Aortic Valve Replacement Interquartile range medicine Humans In patient education Aged Retrospective Studies education.field_of_study Scleroderma Systemic business.industry Retrospective cohort study Aortic Valve Stenosis Middle Aged medicine.disease Surgery Stenosis Treatment Outcome Female medicine.symptom Cardiology and Cardiovascular Medicine business Cohort study |
| Zdroj: | EuroIntervention. 10:1464-1467 |
| ISSN: | 1774-024X |
| DOI: | 10.4244/eijv10i12a255 |
| Popis: | Aims: The aim of this study was to report the feasibility and the preliminary outcomes after transcatheter aortic valve implantation (TAVI) in the frail and unique high-risk population of patients with systemic sclerosis (SSc) and severe aortic stenosis (AS). Methods and results: All patients with SSc and severe AS treated with TAVI between November 2007 and June 2013 in our centre were included in the current study. Outcomes were assessed using the Valve Academic Research Consortium 2 (VARC-2) definitions. Of 526 surgical high-risk patients treated in the study period, only six had SSc (1.1%). All SSc patients underwent transfemoral TAVI under conscious sedation. The procedure was successfully performed in all patients. There was one case of a major vascular complication. During a median follow-up time of 550 days (interquartile range 390-1,009 days), five of the six patients were alive, free from any complications and with an NYHA Class I or II. One patient died at 670 days from a stroke of unknown aetiology. Conclusions: The present case series suggests that the TAVI procedure is feasible in patients with SSc and severe AS. OI Giustino, Gennaro/0000-0002-5400-9516 |
| Databáze: | OpenAIRE |
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