Detection of single gold nanoparticles using spatial modulation spectroscopy implemented with a galvo-scanning mirror system
| Autor: | Shun S. Lo, Mary Sajini Devadas, Todd A. Major, Zhongming Li, Kuai Yu, Gregory V. Hartland, Paul Johns, Nicolas Havard |
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| Rok vydání: | 2013 |
| Předmět: |
Microscope
Materials science Laser scanning business.industry ComputerApplications_COMPUTERSINOTHERSYSTEMS Diffraction efficiency Atomic and Molecular Physics and Optics law.invention Mirror galvanometer Optics Optical microscope law Microscopy Electrical and Electronic Engineering Spectroscopy business Engineering (miscellaneous) Beam (structure) |
| Zdroj: | Applied Optics. 52:7806 |
| ISSN: | 2155-3165 1559-128X |
| DOI: | 10.1364/ao.52.007806 |
| Popis: | The optical extinction of single nanoparticles can be sensitively detected by spatial modulation spectroscopy (SMS), where the particle is moved in and out of a tightly focused laser beam with a piezo-device. Here we show that high sensitivity can be obtained by modulating the beam with a galvo-mirror system, rather than by moving the sample. This work demonstrates an inexpensive method for making a SMS microscope, and shows how an existing laser scanning microscope can be adapted for SMS measurements. The galvo-mirror technique also allows SMS measurements to be performed in a liquid, which is difficult to do with piezo-modulation. |
| Databáze: | OpenAIRE |
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