Clinical relevance of residual disease monitoring by polymerase chain reaction in patients with ALL-1/AF4 positive acute lymphoblastic leukemia

Autor:	Giuliana Alimena, M. C. Rapanotti, Anna Rivolta, Eli Canaani, Giuseppe Cimino, Loredana Elia, Luciana Annino, Francesco Lo Coco, Vincenzo Rossi, Andrea Biondi
Jazyk:	angličtina
Rok vydání:	1996
Předmět:	Male Neoplasm Residual Adult Antineoplastic Agents Base Sequence Chromosomes Human Pair 11 Chromosomes Human Pair 4 DNA-Binding Proteins Female Histone-Lysine N-Methyltransferase Humans Infant Longitudinal Studies Middle Aged Molecular Sequence Data Myeloid-Lymphoid Leukemia Protein Nuclear Proteins Polymerase Chain Reaction Precursor Cell Lymphoblastic Leukemia-Lymphoma Prognosis RNA-Directed DNA Polymerase Recombinant Fusion Proteins Retrospective Studies Translocation Genetic Proto-Oncogenes Transcription Factors Disease law.invention law Pair 11 Polymerase chain reaction Hematology Real-time polymerase chain reaction Pair 4 Residual Transcriptional Elongation Factors Human medicine.medical_specialty Translocation Chromosomes Text mining Genetic Internal medicine Acute lymphocytic leukemia medicine Clinical significance business.industry Consolidation Chemotherapy medicine.disease Minimal residual disease Surgery Neoplasm business Settore MED/15 - Malattie del Sangue
Zdroj:	Scopus-Elsevier
Popis:	In this study we used reverse transcriptase-polymerase chain reaction (RT-PCR) for the longitudinal monitoring of minimal residual disease in 12 patients with All-1/AF-4 positive ALL. Of these, seven also showed at presentation a typical t(4;11) cytogenetic translocation. Seven patients were infants
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb86cbdd6267310dabdaddd7d3a3e06a http://hdl.handle.net/11573/32597 Zobrazit plný text záznamu