Theories of prostatitis etiology

Autor: Michel A. Pontari, Matthew E. Karlovsky
Rok vydání: 2002
Předmět:
Zdroj: Current Urology Reports. 3:307-312
ISSN: 1534-6285
1527-2737
DOI: 10.1007/s11934-002-0055-y
Popis: Prostatitis reflects a broad spectrum of prostatic infections, both acute and chronic. Chronic prostatitis, known as National Institutes of Health category III or chronic pelvic pain syndrome, broadly defines a disease that is still poorly understood, and as a consequence, difficult to treat. Typical symptoms include pelvic pain and voiding dysfunction. Infection is often cited as the cause of this condition, despite frequent negative cultures. A close look at the local prostatic microenvironment may yield clues. The role of inflammatory mediators and what stimulates them can point to potential sites of prevention. A genetic link or relationship to other diseases may prove to be part of the cause. Furthermore, a neurologic source, whether anatomic or psychologic, has been strongly debated. Ultimately, it may become clear that chronic prostatitis represents the final common result of a disease that originates from a cascade of multiple stimuli.
Databáze: OpenAIRE