Paraneoplastic thrombocytosis-induced systemic thromboembolism in a cat
Autor: | D D Sisson, Daniel F. Hogan, R S Dhaliwal, B E Kitchell |
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Rok vydání: | 1999 |
Předmět: |
Male
Pathology medicine.medical_specialty Lung Neoplasms Paraneoplastic Syndromes Aorta Thoracic Disease Neutropenia Cat Diseases Diagnosis Differential Fatal Outcome Bone Marrow Thromboembolism medicine.artery medicine Animals Small Animals Lung Thrombocytosis Aorta Leukopenia medicine.diagnostic_test Euthanasia business.industry medicine.disease Radiography Cats Histopathology Myelopoiesis medicine.symptom business Electrocardiography |
Zdroj: | Journal of the American Animal Hospital Association. 35:483-486 |
ISSN: | 1547-3317 0587-2871 |
DOI: | 10.5326/15473317-35-6-483 |
Popis: | A six-year-old cat presented with clinical signs consistent with distal aortic thromboembolism while clinical signs of cardiovascular disease were absent. Diagnostics, including thoracic radiographs, electrocardiography, and echocardiography revealed no cardiovascular anomalies. Thoracic radiographs revealed multifocal pulmonary lesions consistent with neoplasia. Complete blood cell count demonstrated a marked thrombocytosis, leukopenia, and neutropenia. Histopathology of the pulmonary lesions confirmed multiple bronchoalveolar carcinomas. Myelodysplasia with megakaryocytic hyperplasia and ineffective myelopoiesis was noted on bone-marrow histopathology from multiple sites. The absence of other causes suggested a paraneoplastic thrombocytosis. The diagnosis of paraneoplastic thrombocytosis-induced thromboembolism was made due to the lack of underlying cardiac disease and the presence of a marked thrombocytosis. The presence of thrombocytosis and thromboembolism associated with neoplasia is discussed. |
Databáze: | OpenAIRE |
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