Experimental cryosurgery on bone: A light and electron microscopical investigation
| Autor: | R. Kuylenstierna, Arthur Nathanson, Matti Anniko, Per-G. Lundquist |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Pathology
medicine.medical_specialty Medullary cavity Chemistry medicine.medical_treatment Mandible General Medicine Anatomy Cryosurgery Bone and Bones General Biochemistry Genetics and Molecular Biology Alveolar Artery law.invention Microscopy Electron medicine.anatomical_structure law Cortex (anatomy) medicine Animals Rabbits Normal appearance Electron microscope General Agricultural and Biological Sciences |
| Zdroj: | Cryobiology. 17:563-570 |
| ISSN: | 0011-2240 |
| DOI: | 10.1016/0011-2240(80)90071-1 |
| Popis: | Three rabbits were treated with cryosurgery on the lateral surface of the mandible. Osteocytes with normal appearance were not detected in the cortex after 2 or 7 days following cryosurgery. In the marrow cavity, cells appeared more resistant and often showed a normal morphology as studied with both light and electron microscopy. The reason why cells survived in the marrow cavity is probably due to a combination of sheltering bone and the near proximity to an intact circulation due to a patent alveolar artery. The uncertain extension of the cold front beyond the cortex may indicate that cryosurgery alone is not suitable if a tumor has invaded the marrow cavity, while more superficially located tumors can be eradicated. However, tumor invasion itself destroys the cortex and thus the marrow cavity will be more readily exposed to the more extensive cryosurgical techniques used in clinical cryosurgery. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|