Induction of PCFT and OATP1A2 via vitamin D receptor activation in vitro is not confirmed in vivo in healthy volunteers after a 10-days treatment with 1,25-dihydroxyvitamin D3
| Autor: | Marti, I, Claro da Silva, T, Spanaus, K, Gubler, C, Kullak-Ublick, GA, Jetter, A |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | 16. Jahreskongress für Klinische Pharmakologie; 20141009-20141010; Köln; DOC14vklipha02 /20140925/ |
| DOI: | 10.3205/14vklipha02 |
| Popis: | Aim: In humans, intestinal uptake of folic acid is mainly mediated by the proton-coupled folate transporter PCFT. In Caco-2 cells, the cellular uptake of folate via PCFT can be increased between 2- and 4-fold by a three-day treatment with 1,25-dihydroxyvitamin D3. Additionally, mRNA content and protein[for full text, please go to the a.m. URL] 16. Jahreskongress für Klinische Pharmakologie |
| Databáze: | OpenAIRE |
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