Gelatin Films Modified with Acidic and Polyelectrolyte Polymers—Material Selection for Soft Gastroresistant Capsules
| Autor: | Małgorzata Sznitowska, Bartosz Maciejewski |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
chemistry.chemical_classification
Materials science food.ingredient disintegration Polymers and Plastics gastroresistant polymers General Chemistry Polymer Gelatin Article Gellan gum Polyelectrolyte gelatin lcsh:QD241-441 chemistry.chemical_compound Differential scanning calorimetry food lcsh:Organic chemistry Cellulose acetate phthalate chemistry Rheology Chemical engineering rheology Adhesive polyelectrolyte |
| Zdroj: | Polymers, Vol 11, Iss 2, p 338 (2019) Polymers Volume 11 Issue 2 |
| ISSN: | 2073-4360 |
| DOI: | 10.3390/polym11020338 |
| Popis: | The following investigation comprised the formation of acid-resistant gelatin-based films, intended for future use in soft-capsule technology. Such film compositions were obtained by including nonionized forms of acid-insoluble polymers in a gelatin-based film-forming mixture. The selected films were additionally modified with small amounts of anionic polysaccharides that have potential to interact with gelatin, forming polyelectrolyte complexes. The obtained film compositions were subjected to, e.g., disintegration tests, adhesiveness tests, differential scanning calorimetry (DSC), and a transparency study. As a result of the performed study, some commercial enteric polymers (acrylates), as well as cellulose acetate phthalate, were selected as components that have the ability to coalesce and form a continuous phase within a gelatin film. The use of a small amount (1.5%) of additional gelling polymers improved the rheological characteristics and adhesive properties of the obtained films, with ί-carrageenan and gellan gum appearing to be the most beneficial. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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