Combined treatment modality in pediatric infratentorial midline high‐grade glioma can lead to long‐term survival: A case study and review of literature
| Autor: | Rabi Narayan Sahu, Sovan Sarang Dhar, Dillip Kumar Parida, Chinzah Lalsangzuala, Suvendu Purkait, S. Majumdar |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Modality (human–computer interaction) pediatric CNS neoplasm business.industry R895-920 Neoplasms. Tumors. Oncology. Including cancer and carcinogens survival Medical physics. Medical radiology. Nuclear medicine Combined treatment midline high‐grade glioma Oncology Long term survival medicine adjuvant chemoradiation Radiology business Lead (electronics) RC254-282 High-Grade Glioma |
| Zdroj: | Precision Radiation Oncology, Vol 5, Iss 3, Pp 213-218 (2021) |
| ISSN: | 2398-7324 |
| DOI: | 10.1002/pro6.1127 |
| Popis: | Central nervous system high‐grade glioma (HGG) occurring in an infratentorial midline location is not commonly found in the pediatric population. Though pediatric HGGs appear similar to their adult counterparts histopathologically, they differ in molecular, genetic, and clinical characteristics. Evidence for the management of HGG is sparse in the literature. Surgery in the form of maximum safe resection is the backbone of management and has been variably supplemented with external beam radiotherapy and cytotoxic chemotherapy. The outcome, though largely dismal, has some positive surprises too. As shown in the presented case, the combined modality of management in a 5‐year‐old female child has resulted in a disease‐free survival of 3.5 years. |
| Databáze: | OpenAIRE |
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